C library for high-throughput sequencing data formats
This library provides HTSlib bindings and a high level Rust API for reading and writing BAM files.
Tools (written in C using htslib) for manipulating next-generation sequencing data
Pysam is a Python package for reading, manipulating, and writing genomics data such as SAM/BAM/CRAM and VCF/BCF files. It's a lightweight wrapper of the HTSlib API, the same one that powers samtools, ...
Note: tabix and bgzip binaries are now part of the HTSlib project.
The http://www.htslib.org/ web site